Glutathione One of the Body’s Most Important Antioxidants

by Dr Craige Golding

Listed below are uses of IV glutathione and an IV glutathione protocol

To elevate glutathione naturally consider NAC (N-acetyl cysteine 500mg 2/d), and or whey protein daily.
Alphalipoic 300-600mg is particularly useful too.

In diabetics or neurological conditions, I often increase the aphalipoic to 600mg twice a day
Certain foods can elevate glutathione as well, which I will list below

The benefits of glutathione are enormous

Uses of I.V. Glutathione and oral liposomal glutathione or NAC and ALANeurologic DisordersCVA, ALS, MS, Parkinson’sHeavy Metal DetoxMercuryIntestinalLiver DetoxPrimary detox substances  Autism spectrumPsychiatric disordersInflammatory lung diseaseVascular disease reversal and prevention

Glutathione Functions

AntioxidantDetoxifyingBinds to toxins to facilitate removal, uses enzyme Glutathione-s-transferase (GST) Mercury  Mycotoxins Cell Signal Immune cells

Glutathione is made up of 3 amino acids :

Cysteine (contains sulfur molecule)
Glycine
Glutamine

I.V. Protocol for Glutathione

Safe
Dosage: 500-2500 mg
A mix in 5-10 ml of sterile water
Push over 3-5 minutes
Repeat 2-3 times per week for the first month, then weekly, for a month, the two weekly as desired

Liposomal glutathione is a great was to supplement glutathione orally :

Liposomal Glutathione  prevents Ox – LDL formation which occurs with low GSH (reduced glutathione)

OxLDL → Foam Cells → Plaque
Rupture → Sudden Obstruction of blood vessel

Anti-oxidant and anti-atherogenic properties of liposomal glutathione: studies in vitro, and in the atherosclerotic apolipoprotein E-deficient mice. Atherosclerosis. 2007;195(2):e61-8.
  • Low Glutathione in the prefronatal cortex at postmortem in individuals with Major depressive disorder, bipolar disorder and schizophrenia
  • Gawryluk JW, et al Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders. The international journal of neuropsychopharmacology 2010:1-8. PubMed: 20633320 
  • S-nitrosoglutathione GSNO ← GSH + NO   
  • Formation of GSNO is a mechanism for storage and transport of nitric oxide
  • A major source of bronchodilatory NO activity
  • Decreased GSNO activity found in asthma
  • Protection from experimental asthma by an endogenous bronchodilator
  • Science. 2005 Jun 10;308(5728):1618-21. PMID: 15919956

Encourage foods that are high glutathione precursors:

Avocados
Potato
Strawberries
Watermelon
NAC
BCAA
Rosemary (increase glutathione transferase by 400%)